This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Copyright Permission Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Gnessi, L. Articles by Spera, G. Search for Related Content PubMed PubMed Citation Articles by Gnessi, L. Articles by Spera, G.

Gonadal Peptides as Mediators of Development and Functional Control of the Testis: An Integrated System with Hormones and Local Environment¹

Dipartimento di Fisiopatologia Medica, Università di Roma "La Sapienza," Rome, Italy

I. Introduction

II. Neurohormones/Neuropeptides

A. GH-releasing hormone (GHRH)

B. Pituitary adenylate cyclase-activating peptide (PACAP)

C. GnRH

D. CRH

E. Oxytocin (OT)

F. Arginine vasopressin (AVP)

G. TRH

H. Somatostatin (SRIF)

I. Opioids

J. Substance-P (SP)

K. Neuropeptide Y (NPY)

III. Peptides Originally Identified in the Male Gonad

A. Inhibin (INH) and activin (ACT)

B. PModS

IV. Growth Factors

A. Insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBs)

B. Transforming growth factor-ß (TGFß)

C. TGF/EGF

D. Fibroblast growth factor (FGF)

E. Platelet-derived growth factor (PDGF)

F. Nerve growth factor (NGF)

G. Steel factor (SLF)

H. Gastrin-releasing peptide (GRP)

V. Immune Derived Cytokines

A. Interleukins (ILs)

B. Tumor necrosis factor- (TNF)

VI. Vasoactive Peptides

A. Endothelin (ET)

B. Angiotensin-II (AT-II)

C. Atrial natriuretic peptide (ANP)

VII. Conclusions and Perspectives