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Endocrine Reviews 20 (6): 805-875
Copyright © 1999 by The Endocrine Society

Current and Potential Drugs for Treatment of Obesity

George A. Bray and Frank L. Greenway

Louisiana State University, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808-4124

I. Introduction
II. Criteria for Evaluating the Efficacy of Antiobesity Treatment
III. Physiological and Pharmacological Mechanisms to Reduce Food Intake
A. Peripherally acting agents
B. Centrally acting agents
IV. Drugs That Alter Metabolism
A. Preabsorptive agents
B. Postabsorptive modifiers of nutrient metabolism
V. Drugs That Increase Energy Expenditure
A. Thyroid hormone
B. Adrenergic thermogenic drugs
VI. Conclusion






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Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1999 by The Endocrine Society