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Section of Endocrinology (V.F., C.D., S.A.), Department of Medicine, Tulane University Medical Center, New Orleans, Louisiana 70112; and Laboratory for Atherosclerosis and Metabolic Research (I.J.), University of California Davis, Sacramento, California 95817
Correspondence: Address all correspondence and requests for reprints to: Vivian A. Fonseca, M.D., Professor of Medicine, Director, Tulane Diabetes Program, Department of Medicine, Section of Endocrinology, Tulane University Medical Center SL53, 1430 Tulane Avenue, New Orleans, Louisiana 70112-2699. E-mail: vfonseca{at}tulane.edu
People with type 2 diabetes are disproportionately affected by cardiovascular disease (CVD), compared with those without diabetes. Traditional risk factors do not fully explain this excess risk, and other "nontraditional" risk factors may be important. This review will highlight the importance of nontraditional risk factors for CVD in the setting of type 2 diabetes and discuss their role in the pathogenesis of the excess CVD morbidity and mortality in these patients. We will also discuss the impact of various therapies used in patients with diabetes on nontraditional risk factors.
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