
View larger version (27K):
[in this window]
[in a new window]
|
Figure 1. Pathways of steroid biosynthesis. The
pathways for synthesis of progesterone and mineralocorticoids
(aldosterone), glucocorticoids (cortisol), androgens (testosterone
and dihydrotestosterone), and estrogens (estradiol) are arranged from
left to right. The enzymatic activities
catalyzing each bioconversion are written in boxes. For
those activities mediated by specific cytochromes P450, the systematic
name of the enzyme ("CYP" followed by a number) is listed in
parentheses. CYP11B2 and CYP17 have multiple activities. The
planar structures of cholesterol, aldosterone, cortisol,
dihydrotestosterone, and estradiol are placed near the corresponding
labels.
|