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Current and Potential Drugs for Treatment of Obesity

Louisiana State University, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808-4124

I. Introduction

II. Criteria for Evaluating the Efficacy of Antiobesity Treatment

III. Physiological and Pharmacological Mechanisms to Reduce Food Intake

A. Peripherally acting agents

B. Centrally acting agents

IV. Drugs That Alter Metabolism

A. Preabsorptive agents

B. Postabsorptive modifiers of nutrient metabolism

V. Drugs That Increase Energy Expenditure

A. Thyroid hormone

B. Adrenergic thermogenic drugs

VI. Conclusion

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